Anis

An SR Burst 2 Iron Defender Rocket Launcher with no main PvE role, used as a Burst Gauge battery in Champions Arena.
She is hard to use in Special Arena because of the SR CP penalty.
She is often given only the battery role, even without skill levels or Overload.

Every 40 hits taken, her own DEF rises sharply. S2 grants herself and the 2 allies with the highest ATK Increased DEF and Equally shares damage taken. Her Burst deals damage to enemies in an area and reduces their DEF. In the meta, her role filling the Burst Gauge with Charge Rocket Launcher normal shots matters more than these skills.

In Champions Arena, use her as a battery that fills the Burst Gauge with normal shots.
Use Quantum Cube as her Harmony Cube to boost how fast she fills Burst Gauge.
She is not meant for story or bosses.

Champions Arena battery teams vary in overall composition, so recent sources lack evidence for a fixed pairing with any specific Nikke.

For a Burst Gauge battery, prioritize Quantum Cube. If she takes frequent hits, supplement with Tempering Cube; for reload, Resilience Cube. If Harmony Cube levels differ a lot, use the higher-level cube over the ranking.

For PvP battery use, aim for 4 Charge Speed lines; 18% or more is usually enough. If she is not a PvE core, you can skip Overload investment.

If you only use her as a battery, you barely need to spend skill books. Raise skills to 4 only if you use the DEF and debuff effects.

Champions Arena Burst Gauge battery. Not a core pick for story, bosses, or Solo Raid.

Her Burst Gauge filling speed is among the best in PvP, so she fills Burst Gauge quickly.
She can join battery teams without skill levels or Overload.

As an SR, she is at a disadvantage in modes with a CP penalty such as Special Arena.
She is rarely a core pick in PvE or Solo Raid.
Her DEF and debuff skills contribute little compared to her PvP battery role.